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KMID : 1145120170150040399
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Asian Journal of Beauty and Cosmetology
2017 Volume.15 No. 4 p.399 ~ p.410
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Effects of Evening Primrose Oil and Evening Primrose?rosemary Mixed Oil on Atopic Dermatitis-induced Animal Model
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Kim Seon-Ju
Park Shin-Hee
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Abstract
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Purpose: This study aimed to explore the possibility of using evening primrose oil (E oil) and evening primrose?rosemary mixed oil (ER oil) as alternative substances for treating atopic dermatitis (AD).
Methods: NC/Nga mice were divided into the control, AD-induced, E oil-treated, and ER oil-treated groups. Each group was treated for 6 days. Thereafter, the effects of anti-oxidation and lipid peroxidation activity (LPA) were analyzed. In addition, tissue biopsy samples were observed under a microscope, immunoglobulin E (IgE) levels were measured, and the effects of mast cell degranulation were assessed.
Results: Compared with the control group, the E oil- and ER oil-treated groups showed increased electron donating activity (EDA) and LPA. The epidermal thicknesses were less in the E oil- and ER oil-treated groups than in the AD-induced group and recovered to a degree similar to that of the control group. Quantitative measurements showed decreased IgE levels in the E oiland ER oil-treated groups compared with those in the AD-induced group. Mast cell degranulation was reduced in the E oil- and ER oil-treated groups compared with that in the AD-induced group.
Conclusion: The study results showed that herb oils such as E oil and ER oil can potentially be used for treating dermatitis and that oils with two or more herb oils improved the results.
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KEYWORD
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Evening primrose oil, Rosemary oil, Atopic dermatitis, Anti-oxidant effects, Aromatherapy
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